靶标:
EDA
产品别名:
ECTD1; ED1; ED1-A1; ED1-A2; EDA-A1; EDA-A2; EDA1; EDA2; HED; HED1; ODT1; STHAGX1; TNLG7C; XHED; XLHED; EDA; ectodysplasin A; ectodysplasin A; ectodysplasin-A; X-linked anhidroitic ectodermal dysplasia protein; oligodontia 1; tumor necrosis factor ligand 7C; 外异蛋白A(EDA); 外胚层发育不良蛋白; 外胚层发育不良蛋白1;
背景信息:
The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],