靶标：
EDNRB
产品别名：
ABCDS； ET-B； ET-BR； ETB； ETB1； ETBR； ETRB； HSCR； HSCR2； WS4A； EDNRB； endothelin receptor type B； endothelin receptor type B； endothelin receptor type B； Hirschsprung disease 2； endothelin receptor non-selective type； endothelin receptor subtype B1； 内皮素B受体； 内皮素受体B(ETRB)；
背景信息：
The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016],
