靶标:
EEF1D
产品别名:
EF-1D; EF1D; FP1047; EEF1D; eukaryotic translation elongation factor 1 delta; eukaryotic translation elongation factor 1 delta; elongation factor 1-delta; EF-1-delta; antigen NY-CO-4; eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein); 延伸因子EF-1δ; 真核翻译延伸因子1δ(EEF1d);
背景信息:
eukaryotic translation elongation factor 1 delta(EEF1D) Homo sapiens This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit, delta, functions as guanine nucleotide exchange factor. It is reported that following HIV-1 infection, this subunit interacts with HIV-1 Tat. This interaction results in repression of translation of host cell proteins and enhanced translation of viral proteins. Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. Related pseudogenes have been defined on chromosomes 1, 6, 7, 9, 11, 13, 17, 19.[provided by RefSeq, Aug 2010],