靶标:
EFNA1
产品别名:
B61; ECKLG; EFL1; EPLG1; GMAN; LERK-1; LERK1; TNFAIP4; EFNA1; ephrin A1; ephrin A1; ephrin-A1; TNF alpha-induced protein 4; eph-related receptor tyrosine kinase ligand 1; epididymis secretory sperm binding protein; gastric cancer metastasis associated long noncoding RNA; immediate early response protein B61; ligand of eph-related kinase 1; tumor necrosis factor, alpha-induced protein 4; 内皮细胞受体蛋白酪氨酸激酶A/肿瘤坏死因子α诱导蛋白4; 肝配蛋白A1(EFNA1);
背景信息:
This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin which binds to the EPHA2, EPHA4, EPHA5, EPHA6, and EPHA7 receptors. Two transcript variants that encode different isoforms were identified through sequence analysis. [provided by RefSeq, Jul 2008],