靶标:
EFNB2
产品别名:
EPLG5; HTKL; Htk-L; LERK5; ephrin-B2; EFNB2; ephrin B2; ephrin B2; ephrin-B2; HTK ligand; eph-related receptor tyrosine kinase ligand 5; ligand of eph-related kinase 5; 肝配蛋白B2(EFNB2);
背景信息:
This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors. [provided by RefSeq, Jul 2008],