靶标:
CELA1
产品别名:
ELA1; CELA1; chymotrypsin like elastase 1; chymotrypsin like elastase 1; chymotrypsin-like elastase family member 1; chymotrypsin like elastase family member 1; elastase 1, pancreatic; elastase-1; pancreatic elastase 1; 弹性蛋白酶1; 胰弹性蛋白酶(ELA1);
背景信息:
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, pancreatic elastase 1 is not expressed in the pancreas. To date, elastase 1 expression has only been detected in skin keratinocytes. Clinical literature that describes human elastase 1 activity in the pancreas or fecal material is actually referring to chymotrypsin-like elastase family, member 3B.