靶标：
EPHA8
产品别名：
EEK； EK3； HEK3； EPHA8； EPH receptor A8； EPH receptor A8； ephrin type-A receptor 8； EPH- and ELK-related kinase； EPH- and ELK-related tyrosine kinase； EPH-like kinase 3； hydroxyaryl-protein kinase； protein-tyrosine kinase； tyrosine-protein kinase receptor EEK； tyrosylprotein kinase； 酪氨酸蛋白激酶受体A8；
背景信息：
This gene encodes a member of the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. The protein encoded by this gene functions as a receptor for ephrin A2, A3 and A5 and plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system. [provided by RefSeq, Jul 2008],
