靶标：
ETV6
产品别名：
TEL； TEL/ABL； THC5； ETV6； ETS variant transcription factor 6； ETS variant transcription factor 6； transcription factor ETV6； ETS-related protein Tel1； ETV6-RUNX1 fusion protein； TEL1 oncogene； ets variant gene 6 (TEL oncogene)； 转录因子ETV6；
背景信息：
This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma. [provided by RefSeq, Sep 2008],
