靶标：
ACSL3
产品别名：
ACS3； FACL3； LACS 3； LACS3； PRO2194； ACSL3； acyl-CoA synthetase long chain family member 3； acyl-CoA synthetase long chain family member 3； fatty acid CoA ligase Acsl3； arachidonate--CoA ligase； fatty-acid-Coenzyme A ligase, long-chain 3； lignoceroyl-CoA synthase； long-chain acyl-CoA synthetase 3； long-chain-fatty-acid--CoA ligase 3； medium-chain acyl-CoA ligase Acsl3；
背景信息：
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in brain, and preferentially utilizes myristate, arachidonate, and eicosapentaenoate as substrates. The amino acid sequence of this isozyme is 92% identical to that of rat homolog. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],
