靶标：
FHIT
产品别名：
AP3Aase； FRA3B； FHIT； fragile histidine triad diadenosine triphosphatase； fragile histidine triad diadenosine triphosphatase； bis(5'-adenosyl)-triphosphatase； AP3A hydrolase； adenosine 5'-monophosphoramidase FHIT； adenylylsulfatase； adenylylsulfate-ammonia adenylyltransferase； diadenosine 5',5'''-P1,P3-triphosphate hydrolase； dinucleosidetriphosphatase； 脆性组氨酸三联体；
背景信息：
This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009],
