靶标:
FKBP1B
产品别名:
FKBP12.6; FKBP1L; OTK4; PKBP1L; PPIase; FKBP1B; FKBP prolyl isomerase 1B; FKBP prolyl isomerase 1B; peptidyl-prolyl cis-trans isomerase FKBP1B; 12.6 kDa FK506-binding protein; 12.6 kDa FKBP; FK506 binding protein 1B, 12.6 kDa; FK506-binding protein 12.6; FK506-binding protein 1B; FKBP-12.6; FKBP-1B; PPIase FKBP1B; calstabin 2; h-FKBP-12; immunophilin FKBP12.6; rotamase; FK506结合蛋白1B(FKBP1B); FKBP1B/FKBP9蛋白;
背景信息:
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms. [provided by RefSeq, Jul 2008],