靶标：
FLG
产品别名：
ATOD2； FLG； filaggrin； filaggrin； filaggrin； epidermal filaggrin； 丝聚合蛋白/中间丝蛋白； 丝聚蛋白(FLG)； 丝聚蛋白/中间丝相关蛋白；
背景信息：
The protein encoded by this gene is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Mutations in this gene are associated with ichthyosis vulgaris.[provided by RefSeq, Dec 2009],
