靶标:
FLT3LG
产品别名:
FL; FLG3L; FLT3L; FLT3LG; fms related receptor tyrosine kinase 3 ligand; fms related receptor tyrosine kinase 3 ligand; fms-related tyrosine kinase 3 ligand; flt3 ligand; fms related tyrosine kinase 3 ligand; FMS样酪氨酸激酶3配体;
背景信息:
Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011],