靶标：
FMO2
产品别名：
FMO1B1； FMO2； flavin containing dimethylaniline monoxygenase 2； flavin containing dimethylaniline monoxygenase 2； flavin-containing monooxygenase 2； FMO, pulmonary； dimethylaniline monooxygenase [N-oxide-forming] 2； dimethylaniline oxidase 2； flavin containing monooxygenase 2 (non-functional)； pulmonary flavin-containing monooxygenase 2； 含黄素单加氧酶2(FMO2)； 肝黄素单加氧酶2；
背景信息：
Dimethylaniline monooxygenase [N-oxide-forming] 2 is an enzyme that in humans is encoded by the FMO2 gene. This gene encodes a flavin-containing monooxygenase family member. It is an NADPH-dependent enzyme that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, some human populations contain an allele (FMO2*2A) with a premature stop codon, resulting in a protein that is C-terminally-truncated, has no catalytic activity, and is likely degraded rapidly. This gene is found in a cluster with other related family members on chromosome 1. Alternative splicing results in multiple transcript variants.
