靶标:
FUT8
产品别名:
CDGF; CDGF1; FUT8; fucosyltransferase 8; fucosyltransferase 8; alpha-(1,6)-fucosyltransferase; GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase; GDP-fucose--glycoprotein fucosyltransferase; alpha1-6FucT; fucosyltransferase 8 (alpha (1,6) fucosyltransferase); glycoprotein 6-alpha-L-fucosyltransferase; 岩藻糖基转移酶8(FUT8); 岩藻糖转移酶8;
背景信息:
This gene encodes an enzyme belonging to the family of fucosyltransferases. The product of this gene catalyzes the transfer of fucose from GDP-fucose to N-linked type complex glycopeptides. This enzyme is distinct from other fucosyltransferases which catalyze alpha1-2, alpha1-3, and alpha1-4 fucose addition. The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. Alternative splicing results in multiple transcript variants.