靶标:
GDI1
产品别名:
1A; GDIL; MRX41; MRX48; OPHN2; RABGD1A; RABGDIA; XAP-4; XLID41; GDI1; GDP dissociation inhibitor 1; GDP dissociation inhibitor 1; rab GDP dissociation inhibitor alpha; GDI-1; guanosine diphosphate dissociation inhibitor 1; oligophrenin-2; protein XAP-4; rab GDI alpha; rab GDP-dissociation inhibitor, alpha; testis secretory sperm-binding protein Li 208a; GDP解离抑制因子1(GDI1); 精神发育迟滞相关蛋白Rab GDIα;
背景信息:
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation. [provided by RefSeq, Jul 2008],