靶标：
GLP1R
产品别名：
GLP-1； GLP-1-R； GLP-1R； GLP1R； glucagon like peptide 1 receptor； glucagon like peptide 1 receptor； glucagon-like peptide 1 receptor； GLP-1 receptor； GLP1 receptor； seven transmembrane helix receptor； 胰高血糖素样肽-1受体/GLP-1受体； 胰高血糖素样肽1受体(GLP1R)；
背景信息：
glucagon like peptide 1 receptor(GLP1R) Homo sapiens This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016],
