靶标：
GMDS
产品别名：
GMD； SDR3E1； GMDS； GDP-mannose 4,6-dehydratase； GDP-mannose 4,6-dehydratase； GDP-mannose 4,6 dehydratase； GDP-D-mannose dehydratase； short chain dehydrogenase/reductase family 3E, member 1； 甘露糖脱水酶GMDS；
背景信息：
GDP-mannose 4,6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020).[supplied by OMIM, Aug 2009],
