靶标:
GPR17
产品别名:
GPR17; G protein-coupled receptor 17; G protein-coupled receptor 17; uracil nucleotide/cysteinyl leukotriene receptor; P2Y-like receptor; R12; UDP/CysLT receptor; G蛋白偶联受体17;
背景信息:
function:Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain.,