靶标:
GRK4
产品别名:
GPRK2L; GPRK4; GRK4a; IT11; GRK4; G protein-coupled receptor kinase 4; G protein-coupled receptor kinase 4; G protein-coupled receptor kinase 4; G protein-coupled receptor kinase 2-like; G蛋白偶联受体激酶4; G蛋白偶联受体激酶4(GRK4);
背景信息:
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013],