靶标：
GPT
产品别名：
AAT1； ALT1； GPT1； GPT； glutamic--pyruvic transaminase； glutamic--pyruvic transaminase； alanine aminotransferase 1； alanine aminotransferase； alanine transaminase； glutamate pyruvate transaminase 1； glutamic--pyruvic transaminase 1； glutamic-alanine transaminase 1； glutamic-pyruvate transaminase (alanine aminotransferase)； 谷丙氨酸氨基转移酶1； 谷丙转氨酶(ALT)；
背景信息：
This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase
