靶标:
CXCL2
产品别名:
CINC-2a; GRO2; GROb; MGSA-b; MIP-2a; MIP2; MIP2A; SCYB2; CXCL2; C-X-C motif chemokine ligand 2; C-X-C motif chemokine ligand 2; C-X-C motif chemokine 2; GRO2 oncogene; MGSA beta; MIP2-alpha; chemokine (C-X-C motif) ligand 2; gro-beta; growth-regulated protein beta; macrophage inflammatory protein 2-alpha; melanoma growth stimulatory activity beta; 巨噬细胞炎症蛋白2( GROβ); 巨噬细胞炎症蛋白2( GROβ); 趋化因子配体2(CXCL2);
背景信息:
function:Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.,online information:CXCL2 entry,pharmaceutical:GRO-beta(5-73) is available under the name Garnocestim as immunomodulator. It is used prior to hematopoietic transplantation for peripheral blood stem cell mobilization and reduction of incidence, duration, and/or severity of chemotherapy induced cytopenias.,PTM:The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells.,similarity:Belongs to the intercrine alpha (chemokine CxC) family.,