靶标:
GSTA1
产品别名:
GST-epsilon; GST2; GSTA1-1; GTH1; GSTA1; glutathione S-transferase alpha 1; glutathione S-transferase alpha 1; glutathione S-transferase A1; 13-hydroperoxyoctadecadienoate peroxidase; GST HA subunit 1; GST class-alpha member 1; S-(hydroxyalkyl)glutathione lyase A1; androst-5-ene-3,17-dione isomerase; glutathione S-alkyltransferase A1; glutathione S-aryltransferase A1; glutathione S-transferase 2; glutathione S-transferase Ha subunit 1; testicular tissue protein Li 80; 谷胱甘肽S转移酶α1; 谷胱甘肽S转移酶α1(GSTa1);
背景信息:
This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. This action is an important step in detoxification of these compounds. This subfamily of enzymes has a particular role in protecting cells from reactive oxygen species and the products of peroxidation. Polymorphisms in this gene influence the ability of individuals to metabolize different drugs. This gene is located in a cluster of similar genes and pseudogenes on chromosome 6. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],