靶标:
GUCA2B
产品别名:
GCAP-II; UGN; GUCA2B; guanylate cyclase activator 2B; guanylate cyclase activator 2B; guanylate cyclase activator 2B; prepro-uroguanylin; uroguanylin; 鸟苷酸环化酶激活因子2B; 鸟苷酸环化酶激活因子2B(GUCA2B);
背景信息:
This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products, including uroguanylin, a member of the guanylin family of peptides and an endogenous ligand of the guanylate cyclase-C receptor. Binding of this peptide to its cognate receptor stimulates an increase in cyclic GMP and may regulate salt and water homeostasis in the intestine and kidneys. [provided by RefSeq, Nov 2015],