靶标：
HFE
产品别名：
HFE1； HH； HLA-H； MVCD7； TFQTL2； HFE； homeostatic iron regulator； homeostatic iron regulator； hereditary hemochromatosis protein； MHC class I-like protein HFE； hereditary hemochromatosis protein HLA-H； high Fe； 遗传性血色病蛋白相关蛋白1；
背景信息：
The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq, Jul 2008],
