靶标：
HLA-DMB
产品别名：
D6S221E； RING7； HLA-DMB； major histocompatibility complex, class II, DM beta； major histocompatibility complex, class II, DM beta； HLA class II histocompatibility antigen, DM beta chain； MHC class II HLA-DMB； MHC class II antigen DMB； MHC class II antigen HLA-DM beta chain； class II histocompatibility antigen, M beta chain； really interesting new gene 7 protein； 组织相容性复合体β（HLA-DMB）； 组织相容性复合体蛋白2（HLA-DMB）；
背景信息：
HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008],
