靶标:
HPR
产品别名:
A-259H10.2; HP; HPR; haptoglobin-related protein; haptoglobin-related protein; haptoglobin-related protein; Haptoglobin-related locus; 结合珠蛋白相关蛋白; 触珠蛋白相关蛋白(HPR);
背景信息:
This gene encodes a haptoglobin-related protein that binds hemoglobin as efficiently as haptoglobin. Unlike haptoglobin, plasma concentration of this protein is unaffected in patients with sickle cell anemia and extensive intravascular hemolysis, suggesting a difference in binding between haptoglobin-hemoglobin and haptoglobin-related protein-hemoglobin complexes to CD163, the hemoglobin scavenger receptor. This protein may also be a clinically important predictor of recurrence of breast cancer.