靶标：
PRMT2
产品别名：
HRMT1L1； PRMT2； protein arginine methyltransferase 2； protein arginine methyltransferase 2； protein arginine N-methyltransferase 2； HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 1； HMT1 hnRNP methyltransferase-like 1； PRMT2 alpha； PRMT2 beta； PRMT2 gamma； histone-arginine N-methyltransferase PRMT2； 蛋白精氨酸甲基转移酶2；
背景信息：
Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4. Acts as a coactivator (with NCOA2 of the androgen receptor (AR-mediated transactivation. Acts as a coactivator (with estrogen of estrogen receptor (ER-mediated transactivation. Enhances PGR, PPARG, RARA-mediated transactivation. May inhibit NF-kappa-B transcription and promote apoptosis. Represses E2F1 transcriptional activity (in a RB1-dependent manner. May be involved in growth regulation.
