靶标:
IFNGR2
产品别名:
AF-1; IFGR2; IFNGT1; IMD28; IFNGR2; interferon gamma receptor 2; interferon gamma receptor 2; interferon gamma receptor 2; IFN-gamma receptor 2; IFN-gamma-R-beta; IFN-gamma-R2; interferon gamma receptor accessory factor-1; interferon gamma receptor beta chain; interferon gamma transducer 1; 干扰素-gamma受体2/干扰素-gamma受体β/IFN-γRβ; 干扰素-gamma受体β/IFN-γRβ;
背景信息:
This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance. [provided by RefSeq, Jul 2008],