靶标:
IGFBP6
产品别名:
IBP6; IGFBP6; insulin like growth factor binding protein 6; insulin like growth factor binding protein 6; insulin-like growth factor-binding protein 6; IBP-6; IGF binding protein 6; IGFBP-6; 胰岛素样生长因子结合蛋白6; 胰岛素样生长因子结合蛋白6(IGFBP6);
背景信息:
function:IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.,PTM:O-linked glycans consist of hexose (probably Gal), N-acetylhexosamine (probably GalNAc) and sialic acid residues. Major glycoforms consist of 8-16 monosaccharides (by homology to IGFBP6 expressed recombinantly in CHO cells).,similarity:Contains 1 IGFBP N-terminal domain.,similarity:Contains 1 thyroglobulin type-1 domain.,