靶标：
IL5RA
产品别名：
CD125； CDw125； HSIL5R3； IL5R； IL5RA； interleukin 5 receptor subunit alpha； interleukin 5 receptor subunit alpha； interleukin-5 receptor subunit alpha； CD125 antigen； IL-5 receptor subunit alpha； IL-5R subunit alpha； interleukin 5 receptor type 3； interleukin 5 receptor, alpha； interleukin-5 receptor alpha chain； 白介素-5受体α链IL-5Rα； 白介素5受体α(IL5Ra)；
背景信息：
The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported. [provided by RefSeq, Jul 2011],
