Levoisomethadone is a synthetic opioid analgesic and antitussive related to methadone. It was used as both an analgesic and antitussive. It binds to and activates both the μ- and δ-opioid receptors, with (S)-isomer being the more potent of its two enantiomers. Levoisomethadone is discontinued (DEA controlled substance). References: KEATS AS, BEECHER HK. Analgesic potency and side action liability in man of heptazone, WIN 1161-2, 6-methyl dihydromorphine, Metopon, levo-isomethadone and pentobarbital sodium, as a further effort to refine methods of evaluation of analgesic drugs. J Pharmacol Exp Ther. 1952 Jun;105(2):109-29. PubMed PMID: 14928215.
纯度:≥98%
CAS:561-10-4