靶标:
IL11RA
产品别名:
CRSDA; IL11RA; interleukin 11 receptor subunit alpha; interleukin 11 receptor subunit alpha; interleukin-11 receptor subunit alpha; IL-11 receptor subunit alpha; IL-11R subunit alpha; interleukin 11 receptor, alpha; interleukin-11 receptor alpha chain; 白介素11受体α(IL11Ra); 白介素11受体α/IL-11Rα;
背景信息:
Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012],