靶标:
KCNJ8
产品别名:
KIR6.1; uKATP-1; KCNJ8; potassium inwardly rectifying channel subfamily J member 8; potassium inwardly rectifying channel subfamily J member 8; ATP-sensitive inward rectifier potassium channel 8; inward rectifier K(+) channel Kir6.1; inwardly rectifying potassium channel KIR6.1; potassium channel, inwardly rectifying subfamily J member 8; potassium voltage-gated channel subfamily J member 8; ATP敏感钾离子通道蛋白;
背景信息:
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. Defects in this gene may be a cause of J-wave syndromes and sudden infant death syndrome (SIDS). [provided by RefSeq, May 2012],