靶标：
KNG1
产品别名：
BDK； BK； HAE6； HK； HMWK； KNG； KNG1； kininogen 1； kininogen 1； kininogen-1； alpha-2-thiol proteinase inhibitor； bradykinin； fitzgerald factor； high molecular weight kininogen； williams-Fitzgerald-Flaujeac factor； T-激肽； 低分子量生长促进因子/激肽原1； 激肽原1(KNG1)； 激肽原1重链； 缓激肽； 高分子量激肽原(HMWK)； 高分子量激肽原轻链；
背景信息：
This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2014],
