靶标：
LAMA3
产品别名：
BM600； E170； JEB2A； JEB2B； JEB2C； LAMNA； LOCS； LAMA3； laminin subunit alpha 3； laminin subunit alpha 3； laminin subunit alpha-3； BM600 150kD subunit； LAM3, alpha-3 subunit； epiligrin 170 kda subunit； epiligrin alpha 3 subunit； kalinin 165kD subunit； kalinin subunit alpha； laminin 5, alpha-3 subunit； laminin A3； laminin, alpha 3 (nicein (150kD), kalinin (165kD), BM600 (150kD), epilegrin)； laminin-5 alpha 3 chain； laminin-5 subunit alpha； laminin-6 subunit alpha； laminin-7 subunit alpha； nicein 150kD subunit； nicein subunit alpha； 层粘蛋白α3； 层粘连蛋白5； 层粘连蛋白α3(LAMa3)；
背景信息：
The protein encoded by this gene belongs to the laminin family of secreted molecules. Laminins are heterotrimeric molecules that consist of alpha, beta, and gamma subunits that assemble through a coiled-coil domain. Laminins are essential for formation and function of the basement membrane and have additional functions in regulating cell migration and mechanical signal transduction. This gene encodes an alpha subunit and is responsive to several epithelial-mesenchymal regulators including keratinocyte growth factor, epidermal growth factor and insulin-like growth factor. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa and laryngoonychocutaneous syndrome. Alternative splicing and alternative promoter usage result in multiple transcript variants. [provided by RefSeq, Dec 2014],
