靶标:
LRP3
产品别名:
LRP3; LDL receptor related protein 3; LDL receptor related protein 3; low-density lipoprotein receptor-related protein 3; 105 kDa low-density lipoprotein receptor-related protein; CTD-2540B15.13; LRP-3; hLRp105; 低密度脂蛋白受体相关蛋白3; 低密度脂蛋白受体相关蛋白3(LRP3);
背景信息:
function:Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. Its precise role is however unclear, since it does not bind to very low density lipoprotein (VLDL) or to LRPAP1 in vitro.,similarity:Belongs to the LDLR family.,similarity:Contains 2 CUB domains.,similarity:Contains 4 LDL-receptor class A domains.,subunit:Binds GGA1 and GGA2.,tissue specificity:Widely expressed. Highly expressed in skeletal muscle and ovary. Expressed at intermediate level in heart, brain, liver, pancreas, prostate and small intestine. Weakly expressed in testis, colon and leukocyte.,