靶标:
LSAMP
产品别名:
IGLON3; LAMP; LSAMP; limbic system associated membrane protein; limbic system associated membrane protein; limbic system-associated membrane protein; IgLON family member 3; 大脑边缘系统相关膜蛋白;
背景信息:
This gene encodes a member of the immunoglobulin LAMP, OBCAM and neurotrimin (IgLON) family of proteins. The encoded preproprotein is proteolytically processed to generate a neuronal surface glycoprotein. This protein may act as a selective homophilic adhesion molecule during axon guidance and neuronal growth in the developing limbic system. The encoded protein may also function as a tumor suppressor and may play a role in neuropsychiatric disorders. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.