靶标:
LUM
产品别名:
LDC; SLRR2D; LUM; lumican; lumican; lumican; KSPG lumican; epididymis secretory sperm binding protein; keratan sulfate proteoglycan lumican; lumican proteoglycan; 基膜聚糖(LUM); 基膜聚糖蛋白;
背景信息:
This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair. [provided by RefSeq, Jul 2008],