靶标：
MAF
产品别名：
AYGRP； CCA4； CTRCT21； c-MAF； MAF； MAF bZIP transcription factor； MAF bZIP transcription factor； transcription factor Maf； Avian musculoaponeurotic fibrosarcoma (MAF) protooncogene； T lymphocyte c-maf long form； c-maf proto-oncogene； proto-oncogene c-Maf； v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog； V-Maf肌肉腱膜纤维肉瘤癌基因同源物(MAF)； 原癌基因cMAF；
背景信息：
The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010],
