靶标:
MAGEA11
产品别名:
CT1.11; MAGE-11; MAGE11; MAGEA-11; MAGEA11; MAGE family member A11; MAGE family member A11; melanoma-associated antigen 11; MAGE-11 antigen; cancer/testis antigen 1.11; cancer/testis antigen family 1, member 11; melanoma antigen family A, 11; melanoma antigen family A11; 黑色素瘤相关抗原11;
背景信息:
MAGE family member A11(MAGEA11) Homo sapiens This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],