靶标：
MAGEB2
产品别名：
CT3.2； DAM6； MAGE-XP-2； MAGEB2； MAGE family member B2； MAGE family member B2； melanoma-associated antigen B2； DSS/AHC critical interval MAGE superfamily 6； MAGE XP-2 antigen； MAGE-B2 antigen； cancer/testis antigen 3.2； cancer/testis antigen family 3, member 2； melanoma antigen family B, 2； melanoma antigen family B2； 黑色素瘤相关抗原B2；
背景信息：
This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region. It is expressed in testis and placenta, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21. [provided by RefSeq, Jul 2008],
