靶标:
MAGEB3
产品别名:
CT3.5; MAGEB3; MAGE family member B3; MAGE family member B3; melanoma-associated antigen B3; MAGE-B3 antigen; cancer/testis antigen family 3, member 5; melanoma antigen family B, 3; melanoma antigen family B3; 黑色素瘤相关抗原B3;
背景信息:
This gene is a MAGE-B subfamily member of the MAGE gene family. MAGE family member proteins direct the expression of tumor antigens recognized on a human melanoma by autologous cytolytic T lymphocytes. There are two known clusters of MAGE genes on chromosome X. The members of the MAGE-A subfamily are located in the Xq28 region, while the members of the MAGE-B subfamily are clustered in the Xp21 region. [provided by RefSeq, Jul 2008],