靶标:
MBL2
产品别名:
COLEC1; HSMBPC; MBL; MBL2D; MBP; MBP-C; MBP1; MBPD; MBL2; mannose binding lectin 2; mannose binding lectin 2; mannose-binding protein C; collectin-1; mannan-binding lectin; mannose-binding lectin (protein C) 2, soluble (opsonic defect); mannose-binding lectin 2, soluble (opsonic defect); 甘露聚糖结合凝集素;
背景信息:
This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases. [provided by RefSeq, Jul 2008],