靶标:
MDFI
产品别名:
I-MF; I-mfa; MDFI; MyoD family inhibitor; MyoD family inhibitor; myoD family inhibitor; inhibitor of MyoD family a; myogenic repressor I-mf; 抑制肌原调节蛋白1;
背景信息:
This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. [provided by RefSeq, Jul 2008],