靶标：
MAP3K1
产品别名：
MAPKKK1； MEKK； MEKK 1； MEKK1； SRXY6； MAP3K1； mitogen-activated protein kinase kinase kinase 1； mitogen-activated protein kinase kinase kinase 1； mitogen-activated protein kinase kinase kinase 1； MAP/ERK kinase kinase 1； MAPK/ERK kinase kinase 1； MEK kinase 1； mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase； MAPK/ERK激酶1； 丝裂原激活蛋白激酶激酶激酶1(MAP3K1)；
背景信息：
The protein encoded by this gene is a serine/threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF-kappa-B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N-terminus and phospho-kinase activity conferred by a kinase domain in its C-terminus. [provided by RefSeq, Mar 2012],
