靶标：
MFNG
产品别名：
MFNG； MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase； MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase； beta-1,3-N-acetylglucosaminyltransferase manic fringe； O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase； β-1,3-N-乙酰葡糖胺基转移酶Manic Fringe(MFNG)； 狂躁基因同源蛋白MFNG；
背景信息：
This gene is a member of the fringe gene family which also includes radical and lunatic fringe genes. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. [provided by RefSeq, Oct 2009],
