靶标：
MSH3
产品别名：
DUP； FAP4； MRP1； MSH3； mutS homolog 3； mutS homolog 3； DNA mismatch repair protein Msh3； divergent upstream protein； epididymis secretory sperm binding protein； hMSH3； mismatch repair protein 1； 错配修复蛋白3；
背景信息：
The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer. [provided by RefSeq, Mar 2011],
