靶标:
MYH8
产品别名:
DA7; MyHC-peri; MyHC-pn; gtMHC-F; MYH8; myosin heavy chain 8; myosin heavy chain 8; myosin-8; fetal-myosin heavy chain; myHC-perinatal; myosin heavy chain, skeletal muscle, perinatal; myosin, heavy chain 8, skeletal muscle, perinatal; myosin, heavy polypeptide 8, skeletal muscle, perinatal; 肌球蛋白8; 肌球蛋白重链8(MYH8);
背景信息:
Myosins are actin-based motor proteins that function in the generation of mechanical force in eukaryotic cells. Muscle myosins are heterohexamers composed of 2 myosin heavy chains and 2 pairs of nonidentical myosin light chains. This gene encodes a member of the class II or conventional myosin heavy chains, and functions in skeletal muscle contraction. This gene is predominantly expressed in fetal skeletal muscle. This gene is found in a cluster of myosin heavy chain genes on chromosome 17. A mutation in this gene results in trismus-pseudocamptodactyly syndrome. [provided by RefSeq, Sep 2009],