靶标：
NBL1
产品别名：
D1S1733E； DAN； DAND1； NB； NO3； NBL1； NBL1, DAN family BMP antagonist； NBL1, DAN family BMP antagonist； neuroblastoma suppressor of tumorigenicity 1； DAN domain family member 1； differential screening-selected gene aberrant in neuroblastoma； neuroblastoma 1, DAN family BMP antagonist； neuroblastoma candidate region, suppression of tumorigenicity 1； 成神经细胞瘤抑制瘤变蛋白1(NBL1)； 神经母细胞瘤抑瘤蛋白1；
背景信息：
This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development. Alternatively spliced transcript variants have been identified for this gene. Read-through transcripts between this locus and the upstream mitochondrial inner membrane organizing system 1 gene (GeneID 440574) have been observed. [provided by RefSeq, May 2013],
